Table 2 |
|||||
|
Univariate Analysis of Allelic Association in SNPs |
|||||
|
Single Nucleotide Polymorphism |
Total # of Alleles (Total = 1644) (N, %) |
Control (Total = 582) (N, %) |
Crohn's Disease (Total = 654) (N, %) |
Ulcerative Colitis (Total = 408) (N, %) |
p-value |
|
|
|||||
|
NOD2 - rs5743293 |
< 0.0011 |
||||
|
|
|||||
|
C |
59 (4) |
8 (1) |
43 (7) |
8 (2) |
< 0.00012 |
|
|
|||||
|
N |
1499 (96) |
546 (99) |
561 (93) |
392 (98) |
0.5093 |
|
|
|||||
|
< 0.0014 |
|||||
|
|
|||||
|
NOD2 - rs2066844 |
< 0.0011 |
||||
|
|
|||||
|
C |
1377 (93) |
466 (97) |
545 (89) |
366 (93) |
< 0.0012 |
|
|
|||||
|
T |
109 (7) |
14 (3) |
67 (11) |
28 (7) |
0.0043 |
|
|
|||||
|
0.0424 |
|||||
|
|
|||||
|
NOD2 - rs2066845 |
< 0.0011 |
||||
|
|
|||||
|
G |
1558 (98) |
560 (99) |
601 (96) |
397 (99) |
< 0.0012 |
|
|
|||||
|
C |
38 (2) |
6 (1) |
27 (4) |
5 (1) |
1.0003 |
|
|
|||||
|
0.0064 |
|||||
|
|
|||||
|
IL-23r - rs11465804 |
0.0221 |
||||
|
|
|||||
|
G |
67 (4) |
30 (5) |
16 (3) |
21 (5) |
0.0102 |
|
|
|||||
|
T |
1545 (96) |
534 (95) |
630 (97) |
381 (95) |
0.9483 |
|
|
|||||
|
0.0194 |
|||||
|
|
|||||
|
1 Global (Fisher's Exact Test) 2 Control versus CD 3 Control versus UC 4 CD versus UC |
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|
Kanaan et al. Journal of Negative Results in BioMedicine 2012 11:7 doi:10.1186/1477-5751-11-7 |
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