Table 2

Serum S100B versus Clinical and MRI variables. Estimated mean change in 24-month serum S100B associated with unit increase in mean value of T1 and T2 lesion load, ventricular and spinal cord volume, adjusted for baseline values of both serum S100B and of MRI parameters. Baseline adjustment ensures that the coefficient assesses the 'effect' of the 24-month MRI parameters value relative to its baseline. * Test of treatment interactions with row variable.

Variable

Coefficient

P-value

95% Confidence Interval (CI)

P-value for treatment modification*: Assignment average dose

24 month T1 load

-4 × 10^-6

0.35

-1 × 10^-5, 4 × 10^-6

0.76

0.59

24 month T2 load

-3 × 10^-6

0.16

-7 × 10^-6, 1 × 10^-6

0.57

0.89

24 month ventricular volume

7 × 10^-7

0.75

-3 × 10^-6, 5 × 10^-6

0.46

0.24

24 month cord volume

-2 × 10^-3

0.54

-9 × 10^-3, 5 × 10^-3

0.58

0.88

Lim et al. Journal of Negative Results in BioMedicine 2004 3:4   doi:10.1186/1477-5751-3-4