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The "Statinth" wonder of the world: a panacea for all illnesses or a bubble about to burst

Nusrat Shafiq1 email, Samir Malhotra1 email, Promila Pandhi1 email and Anil Grover2 email

Department of Pharmacology, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India

Department of Cardiology, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India

author email corresponding author email

Journal of Negative Results in BioMedicine 2005, 4:3doi:10.1186/1477-5751-4-3

Published: 23 March 2005

Abstract

After the introduction of statins in the market as effective lipid lowering agents, they were shown to have effects other than lipid lowering. These actions were collectively referred to as 'pleiotropic actions of statins.' Pleiotropism of statins formed the basis for evaluating statins for several indications other than lipid lowering. Evidence both in favour and against is available for several of these indications. The current review attempts to critically summarise the available data for each of these indications.


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