Table 2 |
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|
Genotype distribution of the PLIN rs4578621 and rs894160 SNP according to BMI categories and diabetes status |
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| rs4578621 |
rs894160 |
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|
|
|
||||||
| CC |
CG+GG |
p |
GG |
GA |
AA |
p |
|
|
|
|
||||||
| Men |
Men |
||||||
|
|
|
||||||
| BMI<25 kg/m2 (228) |
194 (85.1) |
34 (14.9) |
109 (47.8) |
97 (42.5) |
22 (9.7) |
||
| 25≤BMI<30 kg/m2 (238) |
204 (85.7) |
34 (14.3) |
ns |
113 (47.5) |
103 (43.3) |
22 (9.2) |
ns |
| BMI≥30 kg/m2 (104) |
91 (87.5) |
13 (12.5) |
58 (55.8) |
36 (34.6) |
10 (9.6) |
||
|
|
|
||||||
| Non-diabetic (397) |
337 (84.9) |
60 (15.1) |
186 (46.9) |
168 (42.3) |
43 (10.8) |
||
| Diabetic (151 M/160 W) |
127 (84.1) |
24 (15.9) |
ns |
82 (51.3) |
62 (38.7) |
16 (10.0) |
ns |
|
|
|
||||||
| Women |
Women |
||||||
|
|
|
||||||
| BMI<25 kg/m2 (249) |
216 (86.8) |
33 (13.2) |
129 (51.8) |
97 (39.0) |
23 (9.2) |
||
| 25≤BMI<30 kg/m2 (172) |
145 (84.3) |
27 (15.7) |
ns |
87 (50.6) |
79(45.9) |
6 (3.5) |
ns |
| BMI≥30 kg/m2 (123) |
103 (83.7) |
20 (16.3) |
58 (47.2) |
54 (43.9) |
11 (8.9) |
||
|
|
|
||||||
| Non-diabetic (439) |
382 (87.0) |
57 (13.0) |
220 (50.1) |
188 (42.8) |
31 (7.1) |
||
| Diabetic (108 M/115 W) |
91 (84.3) |
17 (15.7) |
ns |
66 (57.4) |
39 (33.9) |
10 (8.7) |
ns |
|
|
|||||||
|
Data are n (%). Among the 1120 individuals genotyped, data on BMI or diabetes status were missing for few subjects. M: men, W: women. |
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|
Meirhaeghe et al. Journal of Negative Results in BioMedicine 2006 5:10 doi:10.1186/1477-5751-5-10 |
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