Table 4

Impact of the PLIN rs894160 SNP on clinical variables in men and women separately

Men

Women

GG

281

GA

235

AA

54

GG

272

GA

231

AA

39

Weight, kg

80.2 ± 14.1

79.2 ± 12.8

81.1 ± 13.2

67.5 ± 14.1

69.9 ± 14.6

67.9 ± 16.8

BMI, kg/m²

26.9 ± 4.3

26.3 ± 4.0

26.3 ± 3.7

26.2 ± 5.3

27.0 ± 5.4

26.7 ± 7.1

Waist, cm

96.5 ± 11.4

95.5 ± 10.2

96.3 ± 10.3

84.7 ± 13.4

87.0 ± 14.1

84.3 ± 16.9

Hip circ., cm

101.7 ± 7.5

101.4 ± 7.3

101.4 ± 7.1

102.9 ± 11.1

104.6 ± 11.8

103.7 ± 15.5

WHR

0.95 ± 0.07

0.94 ± 0.07

0.95 ± 0.07

0.82 ± 0.08

0.83 ± 0.08

0.81 ± 0.07

Leptin, ng/mL^†

9.60 ± 7.90

9.18 ± 7.55

8.24 ± 6.19

23.12 ± 13.72

25.26 ± 14.52

23.79 ± 13.28

Cholesterol, mmol/L

5.93 ± 1.10

5.83 ± 1.00

5.86 ± 0.90

5.90 ± 1.18

6.01 ± 1.05

5.93 ± 1.11

HDL-chol., mmol/L

1.33 ± 0.41

1.37 ± 0.41

1.24 ± 0.37

1.65 ± 0.51

1.68 ± 0.47

1.69 ± 0.43

LDL-chol., mmol/L

3.90 ± 1.05

3.79 ± 0.96

3.99 ± 0.85

3.69 ± 1.10

3.80 ± 0.99

3.68 ± 1.05

Triglycerides, mmol/L^†

1.71 ± 1.42

1.57 ± 1.31

1.68 ± 1.66

1.21 ± 0.87

1.19 ± 0.97

1.16 ± 0.77

Glucose, mmol/L^†

5.56 ± 0.90

5.49 ± 0.85

5.27 ± 0.64*

5.40 ± 1.41

5.42 ± 1.71

5.64 ± 1.55

Insulin, μU/mL^†

12.52 ± 9.48

11.93 ± 8.16

12.83 ± 13.62

11.47 ± 5.86

11.83 ± 5.87

12.43 ± 7.32

*crude p < 0.03 or p < 0.04 when adjusted for age, BMI, smoking and alcohol consumptions with a recessive model (adjusted means 5.51 ± 0.05 for GG vs 5.52 ± 0.05 for GA vs 5.28 ± 0.11 for AA subjects). ^† These variables were log-transformed to obtain normal distributions. Circ. : circumference. WHR : waist-to-hip ratio. Chol. : cholesterol. Among the 1120 individuals genotyped, data on several variables were missing for few subjects.

Meirhaeghe et al. Journal of Negative Results in BioMedicine 2006 5:10   doi:10.1186/1477-5751-5-10