Table 1 |
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|
Baseline characteristics in control and Chagas' disease groups. |
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|
Variables |
Group 1 N = 16 |
Group 2 n = 18 |
Group 3 n = 19 |
Control n = 31 |
P value |
|
|
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|
Age (years) |
49.7 ± 5.9 |
47.4 ± 9.3 |
49 ± 10 |
45.3 ± 8.9 |
0.33 |
|
Male sex |
6 (37.5 %) |
6 (33.3 %) |
8 (42 %) |
15 (48.4 %) |
0.30 |
|
Systolic blood pressure (mm Hg) |
120.5 ± 6.8 |
118.9 ± 11.3 |
116.6 ± 11.3 |
118.1 ± 10.3 |
0.72 |
|
Diastolic blood pressure (mm Hg) |
79.8 ± 2.9 |
80 ± 5 |
77.6 ± 5.8 |
76.7 ± 7 |
0.29 |
|
Heart rate (bpm) |
74.6 ± 5.7 |
67.7 ± 7.6 |
74 ± 12 |
71.8 ± 10 |
0.13 |
|
Body mass index (Kg/m2) |
25.8 ± 4.3 |
24.4 ± 3.3 |
23.4 ± 4.5 |
25.4 ± 3.7 |
0.26 |
|
Total cholesterol (mmol/L) |
208 ± 20.8 |
197 ± 21 |
190 ± 34 |
196.3 ± 17.8 |
0.28 |
|
HDL (mmol/L) |
46.4 ± 8.4 |
48.4 ± 9.8 |
46.8 ± 15.4 |
50.3 ± 9.8 |
0.75 |
|
LDL (mmol/L) |
139 ± 20.3 |
130.4 ± 15.4 |
131.7 ± 27.6 |
130.8 ± 16 |
0.68 |
|
Triglycerides (mmol/L) |
131.4 ± 59.6 |
117.1 ± 49.8 |
128 ± 4 |
128.5 ± 49.2 |
0.89 |
|
Hematocrit |
41.2 ± 4 |
42 ± 3 |
40 ± 3 |
39.8 ± 2.9 |
0.20 |
|
Hemoglobin (g/dl) |
14.4 ± 1.2 |
14.5 ± 0.7 |
14 ± 1.2 |
14 ± 0.8 |
0.37 |
|
Serum glucose (g/dL) |
98 ± 9.5 |
93.3 ± 6.4 |
101 ± 12.7 |
93.4 ± 9.3 |
0.12 |
|
Serum sodium (mEq/L) |
140 ± 1.6 |
139.7 ± 1.6 |
139.3 ± 2.6 |
139.7 ± 2 |
0.75 |
|
Blood urea nitrogen (mg/dL) |
32.8 ± 5.3 |
33.8 ± 5 |
38.8 ± 13.6 |
32.7 ± 4.6 |
0.20 |
|
Serum creatinine (mg/dL) |
0.95 ± 0.1 |
0.97 ± 0.2 |
1.05 ± 0.2 |
0.96 ± 0.1 |
0.25 |
|
End diastolic diameter (cm) |
4.7 ± 0.43 |
4.87 ± 0.44 |
6.36 ± 1.09 |
_ |
< 0.00001 |
|
End systolic diameter (cm) |
3.18 ± 0.39 |
3.18 ± 0.4 |
5.11 ± 1.2 |
_ |
< 0.00001 |
|
Ejection fraction |
69.6 ± 5.2 |
70.3 ± 6.3 |
48.7 ± 11 |
_ |
< 0.00001 |
|
Fractional shortening |
33 ± 3.9 |
33.7 ± 5 |
20.9 ± 6.7 |
_ |
< 0.00001 |
|
VO2 (ml/Kg/min) |
20 ± 4.3 |
21.7 ± 7.3 |
14.9 ± 2.1 |
_ |
0.003 |
|
|
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|
VO2 = peak oxygen consumption. |
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Villacorta et al. Journal of Negative Results in BioMedicine 2006 5:9 doi:10.1186/1477-5751-5-9 |
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