Figure 3.

Myelin Membrane Packing in Optic and Sciatic Nerves from Hexb+/- and Hexb-/- Mice. The integral widths w² are plotted as a function of h⁴ to determine the relative amount of myelin packing disorder according to the theory of paracrystalline diffraction [18]. The projected intercept on the ordinate axis is inversely related to the number of repeating units N (the coherent domain size), and the slope is proportional to the fluctuation in period, Δ (lattice or stacking disorder). There were no differences within 95% confidence levels between the Hexb+/- (open symbols, dashed line) and Hexb-/- (filled symbols, solid line) slopes of the optic (circles) or sciatic (squares) nerves (n = 3–8) indicating no change in the membrane packing of the internodal compact myelin for the sciatic nerves (PNS) and for the optic nerves (CNS).