Table 3 |
||
|
Clinico-pathological characteristics of the study group |
||
| Variable* |
Patients |
% |
|
|
||
| Gender |
||
| Males |
573 |
57.2 |
| Females |
429 |
42.8 |
| Family History |
||
| Yes |
167 |
16.7 |
| No |
826 |
82.4 |
| Unknown |
9 |
0.9 |
| Multi-primary Melanoma |
||
| Yes |
152 |
15.2 |
| No |
849 |
84.7 |
| Unknown |
1 |
0.1 |
| Stage at Diagnosis |
||
| 0 |
58 |
5.8 |
| I |
504 |
50.3 |
| II |
235 |
23.4 |
| III |
169 |
16.9 |
| IV |
9 |
0.9 |
| Unstagable¥ |
27 |
2.7 |
| Current Stage |
||
| 0 |
56 |
5.6 |
| I |
435 |
43.4 |
| II |
159 |
15.9 |
| III |
217 |
21.7 |
| IV |
129 |
12.9 |
| Unstagable¥ |
6 |
0.5 |
| Primary Clark Level |
||
| I |
58 |
5.8 |
| II |
108 |
10.8 |
| III |
150 |
14.9 |
| IV |
489 |
48.8 |
| V |
69 |
6.9 |
| Unknown |
128 |
12.8 |
| Thickness (mm) |
||
| In situ |
58 |
5.8 |
| < 1.01 |
321 |
32.0 |
| 1.01 – 2.00 |
272 |
27.1 |
| 2.01 – 4.00 |
161 |
16.1 |
| > 4.00 |
121 |
12.1 |
| Unknown |
69 |
6.9 |
| Tumor Infiltrating Lymphocytes (TILs) |
||
| Absent |
206 |
20.6 |
| Non-brisk |
397 |
39.6 |
| Brisk |
31 |
3.1 |
| unknown |
368 |
36.7 |
| Distant Metastasis |
||
| Yes |
130 |
13.0 |
| No |
870 |
86.8 |
| N/Aϕ |
2 |
0.2 |
| Intransit Metastasis |
||
| No |
942 |
94.0 |
| Yes |
27 |
2.7 |
| N/Aϕ |
33 |
3.3 |
| Number of Moles |
||
| None |
260 |
25.9 |
| Few |
498 |
49.7 |
| Moderate |
169 |
16.9 |
| Many |
40 |
4.0 |
| N/Aϕ |
35 |
3.5 |
| Phenotypic Index |
||
| 1 (low risk) |
38 |
3.8 |
| 2 |
210 |
21.0 |
| 3 |
317 |
31.6 |
| 4 |
328 |
32.7 |
| 5 (high risk) |
105 |
10.5 |
| N/Aϕ |
4 |
0.4 |
| Site of the Primary Melanoma |
||
| Extremities |
535 |
53.4 |
| Trunk |
342 |
34.1 |
| Head and Neck |
71 |
7.1 |
| Non-cutaneousω |
12 |
1.2 |
| Unknown |
42 |
4.2 |
|
|
||
|
* With the exception of 'current stage', the variables were recorded at the initial diagnosis. ¥ patients with missing data on the 'T' classification. ω 90% mucosal melanomas and 10% other sites. ϕ N/A: data not available. |
||
|
Cotignola et al. Journal of Negative Results in BioMedicine 2007 6:9 doi:10.1186/1477-5751-6-9 |
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