Figure 1.

A. Overview over previously published effects of methamphetamine (MA) and methylphenidate (MP) on the dopaminergic fiber densities in the amygdala and the medial prefrontal cortex (PFC) of animals from enriched (ER) an impoverished rearing (IR) conditions. Values were nominated to account for possible variations in the data due to different experimenters and procedures to make them comparable. B. Effect of transfer to enriched environment on the dopaminergic fiber density. There was no significant effect in any of the investigated areas. (Therefore data from different laminae of the PFC was combined here). Abbr.: DA: Dopamine; ER. Enriched environment; IR: Impoverished environment; MA: Methamphetamine, MP: Methylphenidate; BLA: Basolateral Amygdala; CA lat. Lateral part of the central amygdala; CA med: Medial part of the central amygdala; PFC: Prefrontal cortex; [1]: Winterfeld et al., 1998; [2]: Dawirs et al., 1994; [3]: Grund et al., 2006; [4]: Busche et al. 2004.