Table 2 |
|||||
|
Genotype frequencies of EDN, ECP, EPO and MBP polymorphisms in AD patients and controls. |
|||||
| Gene |
Polymorphism |
Genotypes |
AD patients |
controls |
p-value |
|
|
|||||
| EDN |
rs2013109 |
C/C |
22 (6.1%) |
23 (7.1%) |
0.66 |
| C/G |
148 (41.0%) |
123 (37.8%) |
|||
| G/G |
191 (52.9%) |
179 (55.1%) |
|||
| rs10132319 |
Not polymorphic |
- |
- |
- |
|
| ECP |
rs2073342 |
A/A |
53 (14.7%) |
57 (17.6%) |
0.45 |
| A/C |
185 (51.2%) |
152 (47.1%) |
|||
| C/C |
123 (34.1%) |
114 (35.3%) |
|||
| rs2073342 |
C/C |
26 (7.2%) |
32 (9.8%) |
0.13 |
|
| C/G |
158 (43.9%) |
120 (36.9%) |
|||
| G/G |
176 (48.9%) |
173 (53.2%) |
|||
| rs2233860 |
C/C |
15 (4.1%) |
19 (5.9%) |
0.55 |
|
| C/G |
123 (34.1%) |
104 (32.1%) |
|||
| G/G |
223 (61.8%) |
201 (62.0%) |
|||
| EPO |
rs11652709 |
C/C |
34 (9.4%) |
35 (10.8%) |
0.42 |
| C/G |
170 (47.2%) |
137 (42.3%) |
|||
| G/G |
156 (43.3%) |
152 (46.9%) |
|||
| rs3785496 |
G/G |
23 (6.4%) |
18 (5.6%) |
0.89 |
|
| G/A |
142 (39.4%) |
130 (40.1%) |
|||
| A/A |
195 (54.2%) |
176 (54.3%) |
|||
| MBP |
rs490358 |
A/A |
29 (8.0%) |
27 (8.3%) |
0.98 |
| A/G |
137 (38.0%) |
121 (37.2%) |
|||
| G/G |
195 (54.0%) |
177 (54.5%) |
|||
| rs3741089 |
T/T |
99 (27.6%) |
99 (30.7%) |
0.66 |
|
| T/C |
184 (51.2%) |
158 (49.1%) |
|||
| C/C |
76 (21.2%) |
65 (20.2%) |
|||
Parwez et al. Journal of Negative Results in BioMedicine 2008 7:9 doi:10.1186/1477-5751-7-9 |
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