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1.

591
Accesses

Commentary   Open Access Highly Accessed

A critique of the WHO TobReg's "Advisory Note" report entitled: "Waterpipe tobacco smoking: health effects, research needs and recommended actions by regulators"

Kamal Chaouachi Journal of Negative Results in BioMedicine 2006, 5:17 (17 November 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 4 comments

2.

373
Accesses

Mini-review   Open Access Highly Accessed

The Mayer-Rokitansky-Küster-Hauser syndrome (congenital absence of uterus and vagina) – phenotypic manifestations and genetic approaches

Daniel Guerrier, Thomas Mouchel, Laurent Pasquier, Isabelle Pellerin Journal of Negative Results in BioMedicine 2006, 5:1 (27 January 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

3.

282
Accesses

Research   Open Access Highly Accessed

Fall risk in an active elderly population – can it be assessed?

Uffe Laessoe, Hans C Hoeck, Ole Simonsen, Thomas Sinkjaer, Michael Voigt Journal of Negative Results in BioMedicine 2007, 6:2 (26 January 2007)

Abstract | Full text | PDF | PubMed

4.

278
Accesses

Research   Open Access

Aortic distensibility measured by pulse-wave velocity is not modified in patients with Chagas' disease

Humberto Villacorta, Luiz Bortolotto, Edmundo Arteaga, Charles Mady Journal of Negative Results in BioMedicine 2006, 5:9 (12 June 2006)

Abstract | Full text | PDF | PubMed

5.

236
Accesses

Brief report   Open Access

Neuropathogenic Escherichia coli K1 does not exhibit proteolytic activities to exert its pathogenicity

Junaid Iqbal, Mehak Rajani, Ruqaiyyah Siddiqui, Naveed Ahmed Khan Journal of Negative Results in BioMedicine 2013, 12:8 (1 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

6.

219
Accesses

Research   Open Access

Circulating rotaviral RNA in children with rotavirus antigenemia

Kamruddin Ahmed, Gulendam Bozdayi, Marcelo T Mitui, Selim Ahmed, Luthful Kabir, Dalgic Buket, Ilknur Bostanci, Akira Nishizono Journal of Negative Results in BioMedicine 2013, 12:5 (1 February 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Rotavirus (RVA) viremia was not found in children with rotavirus diarrhea, and could not be identified via the presence of antigenemia in the patients’ serum.

7.

218
Accesses

Research   Open Access

Effect of venlafaxine on bone loss associated with ligature-induced periodontitis in Wistar rats

Rosimary S Carvalho, Carolina M de Souza, Julliana CS Neves, Sergio A Holanda-Pinto, Lívia MS Pinto, Gerly AC Brito, Geanne M de Andrade Journal of Negative Results in BioMedicine 2010, 9:3 (14 June 2010)

Abstract | Full text | PDF | PubMed

8.

201
Accesses

Research   Open Access

Searching for plasticity in dissociated cortical cultures on multi-electrode arrays

Daniel A Wagenaar, Jerome Pine, Steve M Potter Journal of Negative Results in BioMedicine 2006, 5:16 (26 October 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 2 comments

9.

198
Accesses

Research   Open Access

Human Endogenous Retrovirus K(HML-2) Gag and Env specific T-cell responses are not detected in HTLV-I-infected subjects using standard peptide screening methods

R Brad Jones, Fabio E Leal, Aaron M Hasenkrug, Aluisio C Segurado, Douglas F Nixon, Mario A Ostrowski, Esper G Kallas Journal of Negative Results in BioMedicine 2013, 12:3 (10 January 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The elicitation of human endogenous retrovirus (HERV)-specific T-cells responses may not have a role in human T-cell leukemia virus type 1 (HTLV-1) associated immunopathology suggests this study.

10.

194
Accesses

Research   Open Access

Prolactin gene expression in primary central nervous system tumors

Graziella Alebrant Mendes, Júlia Fernanda Semmelmann Pereira-Lima, Maria Beatriz Kohek, Geraldine Trott, Marlise Di Domenico, Nelson Pires Ferreira, Miriam da Costa Oliveira Journal of Negative Results in BioMedicine 2013, 12:4 (14 January 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Quantitative real-time polymerase chain reaction (PCR-RT) did not show prolactin expression in primary central nervous system tumors, suggesting that its presence is not a reflex of local production.

11.

192
Accesses

Research   Open Access Highly Accessed

Evaluation of vardenafil for the treatment of subjective tinnitus: a controlled pilot study

Birgit Mazurek, Heidemarie Haupt, Agnieszka J Szczepek, Jörg Sandmann, Johann Gross, Burghard F Klapp, Holger Kiesewetter, Ulrich Kalus, Timo Stöver, Philipp P Caffier Journal of Negative Results in BioMedicine 2009, 8:3 (17 February 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

12.

190
Accesses

Research   Open Access

Exclusion of eleven candidate genes for ocular melanosis in cairn terriers

Paige A Winkler, Joshua T Bartoe, Celeste R Quinones, Patrick J Venta, Simon M Petersen-Jones Journal of Negative Results in BioMedicine 2013, 12:6 (1 March 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The genotyping of eleven candidate genes for Ocular Melanosis in Cairn Terriers suggests they are unlikely to be the gene locus for this condition, highlighting the need for further study.

13.

188
Accesses

Research   Open Access

Maternal undernutrition does not alter Sertoli cell numbers or the expression of key developmental markers in the mid-gestation ovine fetal testis

Luis P Andrade, Stewart M Rhind, Michael T Rae, Carol E Kyle, Jamie Jowett, Richard G Lea Journal of Negative Results in BioMedicine 2013, 12:2 (8 January 2013)

Abstract | Full text | PDF | PubMed

14.

186
Accesses

Commentary   Open Access Highly Accessed

Divine intervention? A Cochrane review on intercessory prayer gone beyond science and reason

Karsten Jørgensen, Asbjørn Hróbjartsson, Peter C Gøtzsche Journal of Negative Results in BioMedicine 2009, 8:7 (10 June 2009)

Abstract | Full text | PDF | PubMed

15.

179
Accesses

Research   Open Access

False rumours of disease outbreaks caused by infectious myonecrosis virus (IMNV) in the whiteleg shrimp in Asia

Saengchan Senapin, Kornsunee Phiwsaiya, Warachin Gangnonngiw, Timothy W Flegel Journal of Negative Results in BioMedicine 2011, 10:10 (3 August 2011)

Abstract | Full text | PDF | PubMed

16.

176
Accesses

Research   Open Access

No effect of 6-month intake of glucosamine sulfate on Modic changes or high intensity zones in the lumbar spine: sub-group analysis of a randomized controlled trial

Philip Wilkens, Kjersti Storheim, Inger Scheel, Linda Berg, Ansgar Espeland Journal of Negative Results in BioMedicine 2012, 11:13 (17 August 2012)

Abstract | Full text | PDF | PubMed

17.

174
Accesses

Research   Open Access Highly Accessed

No connection between the level of exposition to statins in the population and the incidence/mortality of acute myocardial infarction: An ecological study based on Sweden's municipalities

Staffan Nilsson, Sigvard Mölstad, Catarina Karlberg, Jan-Erik Karlsson, Lars-Göran Persson Journal of Negative Results in BioMedicine 2011, 10:6 (24 May 2011)

Abstract | Full text | PDF | PubMed

18.

175
Accesses

Research   Open Access Highly Accessed

The female menstrual cycle does not influence testosterone concentrations in male partners

Jakob O Strom, Edvin Ingberg, Emma Druvefors, Annette Theodorsson, Elvar Theodorsson Journal of Negative Results in BioMedicine 2012, 11:1 (3 January 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The hypothesis that male testosterone concentrations increase with female olfactory ovulation cues is contradicted in a study which monitored thirty couples and established no significant effect, also suggesting no relevance of ovulation to male sexual drive and aggressiveness.

19.

174
Accesses

Mini-review   Open Access Highly Accessed

The "Statinth" wonder of the world: a panacea for all illnesses or a bubble about to burst

Nusrat Shafiq, Samir Malhotra, Promila Pandhi, Anil Grover Journal of Negative Results in BioMedicine 2005, 4:3 (23 March 2005)

Abstract | Full text | PDF | PubMed | 1 comment

20.

165
Accesses

Research   Open Access Highly Accessed

Body composition in male elite athletes, comparison of bioelectrical impedance spectroscopy with dual energy X-ray absorptiometry

Ulla Svantesson, Martina Zander, Sofia Klingberg, Frode Slinde Journal of Negative Results in BioMedicine 2008, 7:1 (22 January 2008)

Abstract | Full text | PDF | PubMed

21.

161
Accesses

Research   Open Access Highly Accessed

Lifestyle counseling during pregnancy and offspring weight development until four years of age: follow-up study of a controlled trial

Taina Mustila, Jani Raitanen, Päivi Keskinen, Antti Saari, Riitta Luoto Journal of Negative Results in BioMedicine 2012, 11:11 (8 May 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Gestational lifestyle counseling does not significantly slow weight gain, proposes this pilot study which investigates risk of childhood obesity.

22.

157
Accesses

Brief report   Open Access

Absence of subtelomeric rearrangements in selected patients with mental retardation as assessed by multiprobe T FISH

Suely Rodrigues dos Santos, Dértia Villalba Freire-Maia Journal of Negative Results in BioMedicine 2012, 11:16 (21 December 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Patients with unexplained mental retardation (MR) and a chromosomal imbalance show an absence of subtelomeric rearrangements when assessed by Multiprobe T Fluorescence In-Situ Hybridization (MT FISH) probe.

23.

157
Accesses

Brief report   Open Access

Comparative measurement of CNP and NT-proCNP in human blood samples: a methodological evaluation

Andreas Kuehnl, Jaroslav Pelisek, Martin Bruckmeier, Wajima Safi, Hans-Henning Eckstein Journal of Negative Results in BioMedicine 2013, 12:7 (1 April 2013)

Abstract | Full text | PDF | PubMed

24.

156
Accesses

Research   Open Access Highly Accessed

Validity of self-reported leisure-time sedentary behavior in adolescents

Olivia Affuso, June Stevens, Diane Catellier, Robert G McMurray, Dianne S Ward, Leslie Lytle, Melinda S Sothern, Deborah R Young Journal of Negative Results in BioMedicine 2011, 10:2 (11 February 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Adolescents generally underestimated the duration of their sedentary behavior compared to data obtained objectively using an accelerometer, a movement monitor capturing the intensity of physical activity, questioning the reliability of activity-based questionnaires in public health research.

25.

152
Accesses

Research   Open Access

Failure of E. coli bacteria to induce preterm delivery in the rat

Emmet Hirsch, Yana Filipovich, Roberto Romero Journal of Negative Results in BioMedicine 2009, 8:1 (4 January 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

26.

149
Accesses

Research   Open Access

Could titanium oxide coating from a sol–gel process make stone baskets more resistant to laser radiation at 2.1 μm?

Jens Cordes, Felix Nguyen, Frank Heidenau, Dieter Jocham Journal of Negative Results in BioMedicine 2012, 11:15 (19 October 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The first attempt at making stone baskets more resistant to laser damage during endoscopic surgery did not result in greater resistance to laser radiation at 2.1 mum.

27.

144
Accesses

Research   Open Access Highly Accessed

Protein kinase A enhances lipopolysaccharide-induced IL-6, IL-8, and PGE2 production by human gingival fibroblasts

Toshiaki Ara, Yoshiaki Fujinami, Hiroko Urano, Kaname Hirai, Toshimi Hatori, Hiroo Miyazawa Journal of Negative Results in BioMedicine 2012, 11:10 (27 March 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Commonly prescribed for bronchial disorders, aminophylline does not adversely affect inflammatory response and exacerbate symptoms in periodontal disease at concentrations used in clinical settings unlike other PKA-inhibiting drugs.

28.

140
Accesses

Research   Open Access Highly Accessed

Effects of lead exposure on hippocampal metabotropic glutamate receptor subtype 3 and 7 in developmental rats

Jian Xu, Huai C Yan, Bo Yang, Lu S Tong, Yu X Zou, Ying Tian Journal of Negative Results in BioMedicine 2009, 8:5 (20 April 2009)

Abstract | Full text | PDF | PubMed

29.

139
Accesses

Research   Open Access Highly Accessed

Soy isoflavones increase preprandial peptide YY (PYY), but have no effect on ghrelin and body weight in healthy postmenopausal women

Martin O Weickert, Manja Reimann, Bärbel Otto, Wendy L Hall, Katherina Vafeiadou, Jesper Hallund, Marika Ferrari, Duncan Talbot, Francesco Branca, Susanne Bügel, Christine M Williams, Hans-Joachim Zunft, Corinna Koebnick Journal of Negative Results in BioMedicine 2006, 5:11 (14 August 2006)

Abstract | Full text | PDF | PubMed

30.

135
Accesses

Research   Open Access

Oxaliplatin neurotoxicity – no general ion channel surface-charge effect

Amir Broomand, Elin Jerremalm, Jeffrey Yachnin, Hans Ehrsson, Fredrik Elinder Journal of Negative Results in BioMedicine 2009, 8:2 (12 January 2009)

Abstract | Full text | PDF | PubMed

31.

135
Accesses

Research   Open Access

Multiple dosing strategies with acetyl L-carnitine (ALCAR) fail to alter age-related hearing loss in the Fischer 344/NHsd rat

Eric C Bielefeld, Donald Coling, Guang-Di Chen, Donald Henderson Journal of Negative Results in BioMedicine 2008, 7:4 (11 July 2008)

Abstract | Full text | PDF | PubMed

32.

134
Accesses

Brief report   Open Access

Effectiveness of low-dose doxycycline (LDD) on clinical symptoms of Sjögren's Syndrome: a randomized, double-blind, placebo controlled cross-over study

Hubertus Seitsalo, Raija K Niemelä, Magdalena Marinescu-Gava, Tuija Vuotila, Leo Tjäderhane, Tuula Salo Journal of Negative Results in BioMedicine 2007, 6:11 (31 December 2007)

Abstract | Full text | PDF | PubMed

33.

132
Accesses

Brief report   Open Access

Role of HOXA7 to HOXA13 and PBX1 genes in various forms of MRKH syndrome (congenital absence of uterus and vagina)

Agnès Burel, Thomas Mouchel, Sylvie Odent, Filiz Tiker, Bertrand Knebelmann, Isabelle Pellerin, Daniel Guerrier Journal of Negative Results in BioMedicine 2006, 5:4 (23 March 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

34.

132
Accesses

Research   Open Access Highly Accessed

Human pluripotent embryonal carcinoma NTERA2 cl.D1 cells maintain their typical morphology in an angiomyogenic medium

Pedro D Simões, Teresa Ramos Journal of Negative Results in BioMedicine 2007, 6:5 (18 April 2007)

Abstract | Full text | PDF | PubMed

35.

132
Accesses

Research   Open Access Highly Accessed

Human haematopoietic stem cells express Oct4 pseudogenes and lack the ability to initiate Oct4 promoter-driven gene expression

Zoe Redshaw, Alastair J Strain Journal of Negative Results in BioMedicine 2010, 9:2 (31 March 2010)

Abstract | Full text | PDF | PubMed

36.

131
Accesses

Research   Open Access Highly Accessed

Vitamin D receptor gene polymorphisms in multiple sclerosis patients in northwest Greece

Chrissa Sioka, Stylianos Papakonstantinou, Sofia Markoula, Foteini Gkartziou, Athanasia Georgiou, Ioannis Georgiou, Sygliti-Henrietta Pelidou, Athanassios P Kyritsis, Andreas Fotopoulos Journal of Negative Results in BioMedicine 2011, 10:3 (5 May 2011)

Abstract | Full text | PDF | PubMed

37.

129
Accesses

Research   Open Access

Histopathological grading of pediatric ependymoma: reproducibility and clinical relevance in European trial cohorts

David W Ellison, Mehmet Kocak, Dominique Figarella-Branger, Giangaspero Felice, Godfraind Catherine, Torsten Pietsch, Didier Frappaz, Maura Massimino, Jacques Grill, James M Boyett, Richard G Grundy Journal of Negative Results in BioMedicine 2011, 10:7 (31 May 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

38.

126
Accesses

Research   Open Access

Applying the Stages of Change model to Type 2 diabetes care in Trinidad: A randomised trial

VA Partapsingh, RG Maharaj, JM Rawlins Journal of Negative Results in BioMedicine 2011, 10:13 (11 October 2011)

Abstract | Full text | PDF | PubMed

39.

128
Accesses

Research   Open Access

Expression of estrogen and progesterone receptors in vestibular schwannomas and their clinical significance

Sushila Jaiswal, Vinita Agrawal, Awadhesh Jaiswal, Rakesh Pandey, Ashok Mahapatra Journal of Negative Results in BioMedicine 2009, 8:9 (4 November 2009)

Abstract | Full text | PDF | PubMed

40.

127
Accesses

Research   Open Access Highly Accessed

Clinical predictors of inflammatory bowel disease in a genetically well-defined Caucasian population

Ziad M Kanaan, Maurice R Eichenberger, Surriya Ahmad, Clayton Weller, Henry Roberts, Jianmin Pan, Shesh N Rai, Robert Petras, E Brooks Weller, Susan Galandiuk Journal of Negative Results in BioMedicine 2012, 11:7 (23 January 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

There is no association between OCTN1 and IGR SNPs and IBD (Inflammatory Bowel Disease), suggests this study which proposes a combined genetic, phenotypic and environmental approach to understand IBD.

41.

125
Accesses

Research   Open Access

TGFBR3 variation is not a common cause of Marfan-like syndrome and Loeys-Dietz-like syndrome

Krishna K Singh, Joerg Schmidtke, Britta Keyser, Mine Arslan-Kirchner Journal of Negative Results in BioMedicine 2012, 11:9 (2 February 2012)

Abstract | Full text | PDF | PubMed

42.

124
Accesses

Research   Open Access Highly Accessed

Diagnosis of tuberculosis: the experience at a specialized diagnostic laboratory

Anita Mashta, Pooja Mishra, Sonia Philipose, S Tamilzhalagan, Hanif Mahmud, Sangeeta Bhaskar, Pramod Upadhyay Journal of Negative Results in BioMedicine 2011, 10:16 (18 November 2011)

Abstract | Full text | PDF | PubMed

43.

124
Accesses

Brief report   Open Access

A polymorphism associated with increased levels of YKL-40 and the risk of early onset of lone atrial fibrillation

Kristoffer M A Henningsen, Morten S Olesen, Golnaz Sajadieh, Stig Haunsoe, Jesper H Svendsen Journal of Negative Results in BioMedicine 2013, 12:1 (2 January 2013)

Abstract | Full text | PDF | PubMed

44.

122
Accesses

Research   Open Access

Peripheral nervous system manifestations in a Sandhoff disease mouse model: nerve conduction, myelin structure, lipid analysis

Melanie A McNally, Rena C Baek, Robin L Avila, Thomas N Seyfried, Gary R Strichartz, Daniel A Kirschner Journal of Negative Results in BioMedicine 2007, 6:8 (10 July 2007)

Abstract | Full text | PDF | PubMed

45.

120
Accesses

Research   Open Access Highly Accessed

Psycho-education programme for temporomandibular disorders: a pilot study

Waseem Jerjes, Geir Madland, Charlotte Feinmann, Mohammed El Maaytah, Mahesh Kumar, Colin Hopper, Tahwinder Upile, Stanton Newman Journal of Negative Results in BioMedicine 2007, 6:4 (23 March 2007)

Abstract | Full text | PDF | PubMed

46.

119
Accesses

Brief report   Open Access

Metallothionein genes: no association with Crohn's disease in a New Zealand population

Angharad R Morgan, Alan G Fraser, Lynnette R Ferguson Journal of Negative Results in BioMedicine 2012, 11:8 (28 January 2012)

Abstract | Full text | PDF | PubMed

47.

117
Accesses

Research   Open Access

Methylphenidate for treating tobacco dependence in non-attention deficit hyperactivity disorder smokers: A pilot randomized placebo-controlled trial

Richard D Hurt, Jon O Ebbert, Ivana T Croghan, Darrell R Schroeder, Amit Sood, J Taylor Hays Journal of Negative Results in BioMedicine 2011, 10:1 (28 January 2011)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Despite similarities in neuropsychologic effects between nicotine and methylphenidate, the first large trial of the psychostimulant in non-ADHD smokers showed neither an increase in smoking abstinence, nor any observed effect on smoking rates and tobacco withdrawal symptoms.

48.

116
Accesses

Research   Open Access

Effects of 60 minutes of hyperoxia followed by normoxia before coronary artery bypass grafting on the inflammatory response profile and myocardial injury

Inga Karu, Peeter Tähepõld, Arno Ruusalepp, Kersti Zilmer, Mihkel Zilmer, Joel Starkopf Journal of Negative Results in BioMedicine 2012, 11:14 (14 September 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Pre-treatment with hyperoxia followed by normoxia before coronary artery bypass grafting does not protect against myocardial injury.

49.

116
Accesses

Research   Open Access

Host factors do not influence the colonization or infection by fluconazole resistant Candida species in hospitalized patients

Yun-Liang Yang, Ming-Fang Cheng, Ya-Wen Chang, Tzuu-Guang Young, Hsin Chi, Sai Cheong Lee, Bruno Cheung, Fan-Chen Tseng, Tun-Chieh Chen, Yu-Huai Ho, Zhi-Yuan Shi, Chung-Huang Chan, Ju-Yu Lin, Hsiu-Jung Lo Journal of Negative Results in BioMedicine 2008, 7:12 (16 December 2008)

Abstract | Full text | PDF | PubMed

50.

114
Accesses

Research   Open Access

Variance in multiplex suspension array assays: carryover of microspheres between sample wells

Brian Hanley Journal of Negative Results in BioMedicine 2007, 6:6 (25 April 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

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