- Bjorn R Olsen, Harvard Medical School
The genotyping of eleven candidate genes for Ocular Melanosis in Cairn Terriers suggests they are unlikely to be the gene locus for this condition, highlighting the need for further study.
Rotavirus (RVA) viremia was not found in children with rotavirus diarrhea, and could not be identified via the presence of antigenemia in the patients’ serum.
Quantitative real-time polymerase chain reaction (PCR-RT) did not show prolactin expression in primary central nervous system tumors, suggesting that its presence is not a reflex of local production.
The elicitation of human endogenous retrovirus (HERV)-specific T-cells responses may not have a role in human T-cell leukemia virus type 1 (HTLV-1) associated immunopathology suggests this study.
Patients with unexplained mental retardation (MR) and a chromosomal imbalance show an absence of subtelomeric rearrangements when assessed by Multiprobe T Fluorescence In-Situ Hybridization (MT FISH) probe.
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Aims & scope
Journal of Negative Results in BioMedicine is an open access, peer-reviewed, online journal that promotes a discussion of unexpected, controversial, provocative and/or negative results in the context of current tenets.
Professor of Developmental Biology at Harvard School of Dental Medicine and the Dean for Research at Harvard School of Dental Medicine
"This is an exciting time for research in the life sciences. Major discoveries providing deep insights into disease mechanisms and the basis for preventive, diagnostic and therapeutic strategies are coming at a fast and furious pace. Problems that only a few years ago were beyond technical limits, can now be successfully addressed and 'old' questions can be re-examined with increasingly powerful methods. Open access journals provide the ideal environment for the rapid dissemination and discussion of all aspects of the results of this research."