Table 3 |
||||
|
Impact of the PLIN rs4578621 SNP on clinical variables in men and women separately |
||||
| Men |
Women |
|||
|
|
|
|||
| CC 487 |
CG+GG 81 |
CC 462 |
CG+GG 80 |
|
|
|
|
|||
| Weight, kg |
79.9 ± 13.6 |
79.6 ± 12.9 |
68.1 ± 14.5 |
70.8 ± 15.2 |
| BMI, kg/m2 |
26.7 ± 4.2 |
26.0 ± 3.6 |
26.4 ± 5.4 |
27.3 ± 5.9 |
| Waist, cm |
96.2 ± 11.0 |
95.2 ± 9.8 |
85.3 ± 13.8 |
87.9 ± 15.0 |
| Hip circ., cm |
101.5 ± 7.4 |
101.6 ± 6.8 |
103.5 ± 11.6 |
105.0 ± 12.7 |
| WHR |
0.95 ± 0.07 |
0.94 ± 0.06 |
0.82 ± 0.08 |
0.83 ± 0.08 |
| Leptin, ng/mL† |
9.48 ± 7.75 |
18.16 ± 6.59 |
24.08 ± 13.90 |
24.17 ± 14.98 |
|
|
|
|||
| Cholesterol, mmol/L |
5.88 ± 1.06 |
5.92 ± 0.94 |
5.92 ± 1.11 |
6.08 ± 1.13 |
| HDL-chol., mmol/L |
1.34 ± 0.42 |
1.31 ± 0.36 |
1.67 ± 0.49 |
1.66 ± 0.49 |
| LDL-chol., mmol/L |
3.86 ± 1.02 |
3.89 ± 0.86 |
3.71 ± 1.04 |
3.90 ± 1.08 |
| Triglycerides, mmol/L † |
1.64 ± 1.38 |
1.69 ± 1.52 |
1.19 ± 0.80 |
1.25 ± 1.37 |
| Glucose, mmol/L † |
5.66 ± 1.37 |
5.52 ± 1.45 |
5.33 ± 1.28 |
5.56 ± 1.41 |
| Insulin, μU/mL † |
12.37 ± 9.35 |
11.95 ± 10.01 |
11.63 ± 6.00 |
12.06 ± 5.84 |
|
† These variables were log-transformed to obtain normal distributions. Circ. : circumference. WHR : waist-to-hip ratio. Chol. : cholesterol. Among the 1120 individuals genotyped, data on several variables were missing for few subjects. | ||||
Meirhaeghe et al. Journal of Negative Results in BioMedicine 2006 5:10 doi:10.1186/1477-5751-5-10 |
||||